Optimizing lipid-lowering therapy for acute coronary syndrome using a decision support system: insights from a cluster randomized trial
Access to a DSS, in hospitals managing ACS, did not improve LLT intensification within 16 weeks or LDL-C goal attainment but revealed a favourable trend towards earlier combination LLT use, which merits larger, longer studies in other settings.
Authors
- Paolo Calabrò (ORCID: https://orcid.org/0000-0002-5018-830X)
- J Lozano
- Rasha Al‐Lamee (ORCID: https://orcid.org/0000-0003-3752-5532)
- Azeem S Sheikh (ORCID: https://orcid.org/0000-0001-7202-9855)
- Alejandro Villanueva
- Françoise Lala
- Jessica L. Smith (ORCID: https://orcid.org/0000-0002-2381-861X)
- Andrea Borin (ORCID: https://orcid.org/0000-0001-8172-3865)
- Rashed Hossain (ORCID: https://orcid.org/0009-0000-5000-3996)
- Leire Unzué (ORCID: https://orcid.org/0000-0002-8372-6901)
- Safa Anwar (ORCID: https://orcid.org/0000-0001-7450-1324)
- Fredrick Frost
- Annie Wright (ORCID: https://orcid.org/0000-0001-9021-4640)
- Dan McKenzie (ORCID: https://orcid.org/0000-0002-2242-0474)
- Satheesh Balakrishnan-Nair
- Jonathan Dao
- Leila Janani (ORCID: https://orcid.org/0000-0003-3829-6364)
- Vivek Kodoth
- Lihang Feng (ORCID: https://orcid.org/0000-0002-5790-0478)
- José López Aguilera (ORCID: https://orcid.org/0000-0001-6160-5044)
- Maria Moreno Morales (ORCID: https://orcid.org/0000-0002-1472-6078)
- Christophe Stevens (ORCID: https://orcid.org/0000-0002-7129-8524)
- Stephanie Amiridis
- José Ramón González‐Juanatey (ORCID: https://orcid.org/0000-0001-9681-3388)
- Alessandro Sionís (ORCID: https://orcid.org/0000-0003-0843-9512)
- Nandita Kaza (ORCID: https://orcid.org/0000-0001-8725-5679)
- Julia Brandts (ORCID: https://orcid.org/0000-0002-1141-1126)
- Victoria Cornelius (ORCID: https://orcid.org/0000-0002-0080-1065)
- Karen Danois
- Manuel Martínez‐Sellés (ORCID: https://orcid.org/0000-0003-0289-6229)
- Gaia Kiru
- Alessandro Sciahbasi (ORCID: https://orcid.org/0000-0002-7964-4479)
- Lorna Hazell (ORCID: https://orcid.org/0000-0002-5962-0648)
- Giuseppe Andò (ORCID: https://orcid.org/0000-0001-5552-6382)
- Raffaele De Caterina (ORCID: https://orcid.org/0000-0003-1637-574X)
- Domingo A. Pascual‐Figal (ORCID: https://orcid.org/0000-0002-4993-9540)
- Gianni Casella (ORCID: https://orcid.org/0000-0002-0701-7329)
- Natale Daniele Brunetti (ORCID: https://orcid.org/0000-0001-9610-7408)
- Neil R Poulter (ORCID: https://orcid.org/0000-0002-6292-997X)
- Jesús Peteiro (ORCID: https://orcid.org/0000-0002-8457-6351)
- Sima Toopchiani (ORCID: https://orcid.org/0009-0003-9271-144X)
- Alberto Zambon (ORCID: https://orcid.org/0000-0001-7096-5201)
- Afzar Zaman
- John W. McEvoy (ORCID: https://orcid.org/0000-0001-6530-5479)
- Kamlesh K. Khunti (ORCID: https://orcid.org/0000-0003-2343-7099)
- Roberta Della Bona (ORCID: https://orcid.org/0000-0003-4146-7099)
- Roberto Martín‐Asenjo (ORCID: https://orcid.org/0000-0001-6776-6922)
- George Hunter
- Helen Routledge (ORCID: https://orcid.org/0000-0003-3602-6619)
- Carlos Arellano Serrano (ORCID: https://orcid.org/0000-0001-8954-9929)
- José López‐Sendón (ORCID: https://orcid.org/0000-0002-0871-9197)
- Fotios Barkas
- Vinoda Sharma (ORCID: https://orcid.org/0000-0001-8439-8850)
- Raúl Moreno (ORCID: https://orcid.org/0000-0002-0717-1174)
- Sharad Agrawal (ORCID: https://orcid.org/0000-0002-2914-4513)
- Derek Connolly (ORCID: https://orcid.org/0000-0002-5471-133X)
- David P Ripley (ORCID: https://orcid.org/0000-0001-8460-9873)
- Mohamed N. Alama (ORCID: https://orcid.org/0000-0001-8152-7661)
- F. Cortés (ORCID: https://orcid.org/0009-0000-9319-3486)
- Smita Das
- José Tuñón
- Claudio Fresco
- Sukhbir Dhamrait
- Joe Martins
- Alessandro Navazio
- Neil R. Poulter
- Nayan Das
- Andrew Moriarty
- Giuseppe Boriani (ORCID: https://orcid.org/0000-0002-9820-4815)
- Vanaja Kakarla
- Christina Elorz
- Yasmin Abdat
- Eloise Britten
Institutions
- University of Padua (IT)
- University of Leicester (GB)
- Ollscoil na Gaillimhe – University of Galway (IE)
- University of Ioannina (GR)
- Public Health England (GB)
- Hospital La Paz Institute for Health Research (ES)
- NIHR Imperial Biomedical Research Centre (GB)
- COPE Galway (IE)
- Metropolitan Hospital (GR)
- Imperial College London (GB)
- RWTH Aachen University (DE)
Publication Details
- Journal
- European Heart Journal - Digital Health
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1093/ehjdh/ztaf135
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00