Differentiating gait behaviors between early-stage dementia with Lewy bodies and Parkinson’s disease
These findings suggest quantitative gait measurements may be a promising, sensitive, and selective biomarker for differentiating clinical patterns of neurodegeneration. An understanding of early disease gait profiles may also prove useful as a tool for tracking phenoconversion to a synucleinopathy in those prodromal patients who are at high risk, such as those with isolated Rapid Eye Movement Sleep Behavior Disorder.
Authors
- Kaylena A. Ehgoetz Martens (ORCID: https://orcid.org/0000-0002-8488-2295)
- Kaitlin Mathias (ORCID: https://orcid.org/0009-0009-0917-1926)
- Elie Matar (ORCID: https://orcid.org/0000-0002-4994-0488)
- Joseph R. Phillips (ORCID: https://orcid.org/0000-0001-8239-7512)
- Simon J.G. Lewis (ORCID: https://orcid.org/0000-0002-4093-7071)
- Luiz Paulo Oliveira Martins (ORCID: https://orcid.org/0000-0001-6223-3107)
- Ana Jéssica Pinto (ORCID: https://orcid.org/0000-0002-1363-7233)
Institutions
- University of Waterloo (CA)
- MIND Research Institute (US)
Publication Details
- Journal
- Gait & Posture
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.gaitpost.2025.110034
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00