Transfusion free Norwood procedure

PurposeTo reduce and avoid the use of exogenous blood products for neonates and infants, our center limits the use of packed red blood cells and does not use fresh frozen plasma in our cardiopulmonary bypass (CPB) circuit primes. This practice has resulted in several bloodless neonatal open heart surgical procedures including the entire post operative hospital stays. This case report describes a patient with Hypoplastic Left Heart Syndrome who underwent the Norwood procedure without the use of exogenous blood products. No other report of a bloodless Norwood procedure could be found in the literature.MethodsMiniaturized cardiopulmonary bypass circuitry, including shortened arterial and venous lines, minimized modified ultrafiltration and cardioplegia circuits, low holdup volume vents and autologous bypass circuit priming, was used to preserve adequate oxygen carrying capacity at CPB initiation and during the entire surgical procedure.OutcomeNo exogenous blood products were administered to this patient during their entire hospitalization.

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Publication Details

Journal
Perfusion
Published
2025-11-20
DOI
https://doi.org/10.1177/02676591251395163
Primary Topic
Congenital Heart Disease Studies
Type
article
Field-Weighted Citation Impact
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article

Transfusion free Norwood procedure

Christina L. Greene, Marie-Louise Phillips, David C. Mauchley, Kevin Charette et al.
Perfusion
Congenital Heart Disease Studies
article

Transfusion free Norwood procedure

Christina L. Greene, Marie-Louise Phillips, David C. Mauchley, Kevin Charette, Lyubomyr Bohuta, Neelam Sharma, Michael R. McMullan, Brian Perfette, Kailey Fuegmann, Amy Falconer-Harris
article en

Abstract

PurposeTo reduce and avoid the use of exogenous blood products for neonates and infants, our center limits the use of packed red blood cells and does not use fresh frozen plasma in our cardiopulmonary bypass (CPB) circuit primes. This practice has resulted in several bloodless neonatal open heart surgical procedures including the entire post operative hospital stays. This case report describes a patient with Hypoplastic Left Heart Syndrome who underwent the Norwood procedure without the use of exogenous blood products. No other report of a bloodless Norwood procedure could be found in the literature.MethodsMiniaturized cardiopulmonary bypass circuitry, including shortened arterial and venous lines, minimized modified ultrafiltration and cardioplegia circuits, low holdup volume vents and autologous bypass circuit priming, was used to preserve adequate oxygen carrying capacity at CPB initiation and during the entire surgical procedure.OutcomeNo exogenous blood products were administered to this patient during their entire hospitalization.

Perfusion
Seattle Children's Hospital (US), Seattle Children's Hospital (US)
Openalex Percentile: Top 54%
Congenital Heart Disease Studies
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