Prehospital Postintubation Hypotension and Survival in Severe Traumatic Brain Injury
In this cohort study of patients with severe TBI who received prehospital rapid sequence induction, postintubation hypotension was associated with increased 30-day mortality. This association was strongest for patients with isolated TBI. These findings suggest the need for randomized prehospital interventional studies to reduce the incidence of postintubation hypotension in traumatic brain injury.
Authors
- Lyle Moncur (ORCID: https://orcid.org/0000-0003-2016-6035)
- Ed Barnard (ORCID: https://orcid.org/0000-0002-5187-1952)
- Rob Major
- Alistair Steel (ORCID: https://orcid.org/0000-0002-4537-8360)
- Peter Sherren (ORCID: https://orcid.org/0000-0003-3885-0564)
- Sarah McLachlan (ORCID: https://orcid.org/0000-0003-2009-0122)
- Kate Lachowycz (ORCID: https://orcid.org/0000-0002-3777-1445)
- Chris Keeliher
- Liam Sagi (ORCID: https://orcid.org/0000-0002-4078-8774)
- Benjamin Finbow
- James Price (ORCID: https://orcid.org/0000-0003-2541-8545)
- Matt Targett
Institutions
- National Health Service (GB)
- NHS Lothian (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- University of Cambridge (GB)
- Royal Navy (GB)
- Edinburgh Royal Infirmary (GB)
- South East Physics Network (GB)
- Thomas Foundation (AU)
- London Ambulance Service NHS Trust (GB)
- Anglia Ruskin University (GB)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.44057
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00