Evaluation of the efficacy of curcuminoids gel as an adjunct to scaling and root planing in the treatment of chronic periodontitis: A clinicobiochemical study

In treating moderate chronic periodontitis, the adjunctive use of curcuminoid gel significantly improved clinical outcomes compared to SRP alone. Following the procedure, the PGE2 level in GCF was substantially lower in the test sites than in the control sites. Controlled release mechanisms lessen inflammation and prevent recolonization for an extended period. Given the limitations of the study, curcuminoid gel may be utilized in addition to nonsurgical periodontal treatment.