<scp>WHO</scp> classification of skin tumours: key updates in the fifth edition
The 5th edition of the World Health Organization Classification of Tumours (WCT) serves as a foundation for global diagnostic standards in tumour pathology. Similar to other volumes in this series, the Skin Tumours (Skin5) edition follows a standardized approach. This edition introduces two new chapters: 'Tumours of the nail unit' and 'Metastases to skin', along with new entities across relevant chapters. This review article provides an overview of the updates in Skin5 based on currently published evidence, with emphasis on newly introduced chapters and newly described entities that involve the skin, in particular, epidermal, melanocytic and appendageal tumours.
Authors
- David E. Elder (ORCID: https://orcid.org/0000-0003-4575-2364)
- Brian Rous (ORCID: https://orcid.org/0000-0002-7619-461X)
- Thomas Brenn (ORCID: https://orcid.org/0000-0002-0089-0352)
- Daniela Massi (ORCID: https://orcid.org/0000-0002-5688-5923)
- Jane L. Messina (ORCID: https://orcid.org/0000-0002-0332-0224)
- Ian A. Cree (ORCID: https://orcid.org/0000-0001-5007-9456)
- Rosalie Elenitsas (ORCID: https://orcid.org/0009-0002-7269-5123)
- Anthony James Gill (ORCID: https://orcid.org/0000-0002-9447-1967)
- Werner Kempf (ORCID: https://orcid.org/0000-0002-6552-8629)
- Raymond L. Barnhill (ORCID: https://orcid.org/0000-0001-8086-8544)
- Lyn M. Duncan (ORCID: https://orcid.org/0000-0003-3732-8256)
- Alexander J. Lazar (ORCID: https://orcid.org/0000-0002-6395-4499)
- Pedram Gerami (ORCID: https://orcid.org/0000-0002-6194-1037)
- Boris C. Bastian (ORCID: https://orcid.org/0000-0003-1836-6062)
- Shahin Sayed (ORCID: https://orcid.org/0000-0002-3472-511X)
- Arnaud de la Fouchardière (ORCID: https://orcid.org/0000-0003-2251-8241)
- Harshima Disvini Wijesinghe (ORCID: https://orcid.org/0000-0002-2847-1440)
- Kátia Ramos Moreira Leite (ORCID: https://orcid.org/0000-0002-2615-7730)
- Jennelle C. Hodge (ORCID: https://orcid.org/0000-0002-1770-4042)
- Wayne Grayson (ORCID: https://orcid.org/0000-0001-6303-6092)
- Puay Hoon Tan (ORCID: https://orcid.org/0000-0002-1052-8605)
- Holger Moch (ORCID: https://orcid.org/0000-0002-7986-2839)
- Eduardo J. Calonje (ORCID: https://orcid.org/0000-0001-7475-6423)
- Gabrielle Goldman‐Lévy (ORCID: https://orcid.org/0000-0002-8289-126X)
- Andrew S Field (ORCID: https://orcid.org/0000-0001-9604-4507)
- Joseph David Khoury (ORCID: https://orcid.org/0000-0003-2621-3584)
- Dilani Lokuhetty (ORCID: https://orcid.org/0000-0002-4275-3436)
- Zhiyong Liang (ORCID: https://orcid.org/0000-0003-4787-2925)
- Rajendra Singh (ORCID: https://orcid.org/0000-0003-4420-5561)
- Dmitry Kazakov (ORCID: https://orcid.org/0009-0003-2985-2311)
Institutions
- Northwestern University (US)
- St Thomas' Hospital (GB)
- The University of Texas MD Anderson Cancer Center (US)
- Universidade de São Paulo (BR)
- University of California, San Francisco (US)
- University of the Witwatersrand (ZA)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Université Paris Cité (FR)
- University of Michigan (US)
- Aga Khan University Hospital Nairobi (KE)
- Hospital of the University of Pennsylvania (US)
- Royal North Shore Hospital (AU)
- Peking Union Medical College Hospital (CN)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- Moffitt Cancer Center (US)
- St Vincent's Hospital Sydney (AU)
- Massachusetts General Hospital (US)
- Sorbonne Paris Cité (FR)
- St Vincent’s Private Hospital Sydney (AU)
- University Hospital of Zurich (CH)
- Centre Léon Bérard (FR)
- Aga Khan University Nairobi (KE)
- Michigan United (US)
- Summit School (US)
- Centre international de recherche sur le cancer (FR)
- Indiana University School of Medicine
- University of Florence (IT)
- Indiana University – Purdue University Indianapolis (US)
- University of Nebraska Medical Center (US)
- Institut Curie (FR)
Publication Details
- Journal
- Histopathology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1111/his.15562
- Citations
- 2
- Primary Topic
- Nonmelanoma Skin Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.71