Adult retroperitoneal Ganglioneuroma: Case report of an incidental mass treated with robotic excision

Retroperitoneal ganglioneuromas are rare, benign neural crest-derived tumors that typically occur in children and infrequently in adults. Their preoperative diagnosis is difficult due to nonspecific imaging findings, requiring histopathological confirmation. We report a 51-year-old man with an incidentally discovered retroperitoneal mass during evaluation for leukocytosis. Imaging showed a 7.8 × 4.5 × 8 cm lesion adjacent to the right kidney and duodenum. The tumor was completely excised through a robotic-assisted approach, and histopathology confirmed ganglioneuroma. This case emphasizes considering ganglioneuroma in the differential diagnosis of retroperitoneal tumors and demonstrates the feasibility and safety of robotic-assisted excision for such lesions.