Breast surgery for metastatic breast cancer
Evidence from five randomised controlled trials suggests that adding breast surgery to the treatment of de novo metastatic breast cancer improves local disease control. Breast surgery does not seem to improve overall survival. However, the effect could vary depending on the immunohistochemical profile; these findings are exploratory and are not definitive. Breast surgery might not affect quality of life, distant progression-free survival or toxicity.
Authors
- Crystian B. Oliveira (ORCID: https://orcid.org/0000-0002-6911-7018)
- Ismael Forte Freitas Júnior (ORCID: https://orcid.org/0000-0002-5071-0428)
- Thaís Reis Silva de Paulo (ORCID: https://orcid.org/0000-0002-0307-9151)
- Maria Regina Torloni (ORCID: https://orcid.org/0000-0003-4944-0720)
- Bruna Salani Mota (ORCID: https://orcid.org/0000-0001-9567-1066)
- Giuliano Tosello (ORCID: https://orcid.org/0000-0002-8947-2009)
- Teresa Neeman (ORCID: https://orcid.org/0000-0002-7315-3695)
- Diego Giulliano Destro Christófaro (ORCID: https://orcid.org/0000-0001-9917-9992)
- Rachel Riera (ORCID: https://orcid.org/0000-0002-9522-1871)
- Marcelo RS Cruz
Institutions
- Australian National University (AU)
- Universidade Federal do Rio Grande do Norte (BR)
- Instituto do Câncer do Estado de São Paulo (BR)
- Universidade do Oeste Paulista (BR)
- Cochrane (BR)
- Hospital Regional de Presidente Prudente (BR)
- Hospital Sírio-Libanês (BR)
- Universidade Estadual Paulista (Unesp) (BR)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- Cochrane Database of Systematic Reviews
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1002/14651858.cd011276.pub3
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00