High prevalence of factor XIII deficiency and its association with bleeding in extracorporeal membrane oxygenation patients: an observational study from a prospectively compiled biobank
In this cohort of adult ECMO patients, we observed a high prevalence of FXIII deficiency. FXIII deficiency was common in adult ECMO patients and associated with viral infections, venovenous ECMO, longer ECMO duration, and bleeding; its therapeutic potential warrants further study.
Authors
- Peter Quehenberger (ORCID: https://orcid.org/0000-0002-0122-8213)
- Michael Schwameis (ORCID: https://orcid.org/0000-0003-2741-6877)
- Roman Brock
- Harald Herkner (ORCID: https://orcid.org/0000-0003-1329-6149)
- Nina Buchtele (ORCID: https://orcid.org/0000-0002-1270-6452)
- Thomas Staudinger (ORCID: https://orcid.org/0000-0003-4311-4473)
- Bernhard Nagler
- Andrea Kornfehl
- Maxwell Eder (ORCID: https://orcid.org/0000-0003-0763-1852)
- Peter Schellongowski
Institutions
- Medical University of Vienna (AT)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.rpth.2025.103254
- Primary Topic
- Blood properties and coagulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00