Stress Biomarkers in Young Adult University Students Before, During, and After the COVID-19 Pandemic: A Longitudinal Cohort Study

The findings highlight the impact of long-term stressors on the biochemical balance of stress-hormones and neurotransmitters and the long-term biological and behavioral effects of the pandemic on university students, with potential consequences for their future somatic and mental health. Physical exercise emerges as an important protective factor against the effects of chronic stress, as does timely mental health monitoring and support.

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Publication Details

Journal
Cureus
Published
2025-11-20
DOI
https://doi.org/10.7759/cureus.97328
Primary Topic
Stress Responses and Cortisol
Type
article
Field-Weighted Citation Impact
0.00
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article

Stress Biomarkers in Young Adult University Students Before, During, and After the COVID-19 Pandemic: A Longitudinal Cohort Study

Mattheos Bobos, Constantine Anetakis, Sotirios Varlamis, Maria Chatzidimitriou et al.
Cureus
Stress Responses and Cortisol
article

Stress Biomarkers in Young Adult University Students Before, During, and After the COVID-19 Pandemic: A Longitudinal Cohort Study

Mattheos Bobos, Constantine Anetakis, Sotirios Varlamis, Maria Chatzidimitriou, Vasileios Papaliagkas, Eleftherios Panteris, Stella Mitka, Ioannis Chaniotakis, Petros Skepastianos, Aikaterini Anetaki
article en

Abstract

The findings highlight the impact of long-term stressors on the biochemical balance of stress-hormones and neurotransmitters and the long-term biological and behavioral effects of the pandemic on university students, with potential consequences for their future somatic and mental health. Physical exercise emerges as an important protective factor against the effects of chronic stress, as does timely mental health monitoring and support.

CureusVol. 17(11)
International Hellenic University (GR), University Hospital of Heraklion (GR)
Openalex Percentile: Top 62%
Stress Responses and Cortisol
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Stress Biomarkers in Young Adult University Students Before, During, and After the COVID-19 Pandemic: A Longitudinal Cohort Study — Mattheos Bobos, Constantine Anetakis, et al. · Cureus (2025) | TGRS Research Map | TGRS