Identification of candidate susceptibility genes for cutaneous malignant melanoma through integrated multi-method analysis
This study identifies TMEM184B as a previously unreported risk gene for CMM and reaffirms the relevance of MAFF in disease predisposition. These findings advance our understanding of melanoma's genetic architecture and highlight specific, high-priority genes and pathways for future experimental investigation, suggesting they may serve as potential therapeutic targets.
Authors
- Xin Jiang (ORCID: https://orcid.org/0000-0002-4613-7438)
- Dan Wang (ORCID: https://orcid.org/0000-0002-6036-3175)
- Wanchun Wang (ORCID: https://orcid.org/0000-0001-5082-4153)
- Ping Zhou
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1007/s12672-025-04006-9
- Primary Topic
- Cutaneous Melanoma Detection and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00