Radiotherapy dose–response of mycosis fungoides with large cell transformation

LCTMF is radio-responsive, with EQD2 >12.0 Gy associated with 100 % ORR. Dose-response was observed, with EQD2 >36.0 Gy achieving 100 % CR rate. For unifocal cutaneous LCTMF, RT-alone achieved excellent infield control with possible curative potential in a proportion of patients.

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Publication Details

Journal
Radiotherapy and Oncology
Published
2025-11-20
DOI
https://doi.org/10.1016/j.radonc.2025.111292
Primary Topic
Cutaneous lymphoproliferative disorders research
Type
article
Field-Weighted Citation Impact
0.00
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article

Radiotherapy dose–response of mycosis fungoides with large cell transformation

Odette Buelens, H. Miles Prince, Michael Fahey, Belinda A. Campbell et al.
Radiotherapy and Oncology
Cutaneous lymphoproliferative disorders research
article

Radiotherapy dose–response of mycosis fungoides with large cell transformation

Odette Buelens, H. Miles Prince, Michael Fahey, Belinda A. Campbell, Friyana Bhabha, Christopher McCormack, Martin Higgins, Carrie van der Weyden, Philippa Johnstone, Stephen Lade
article en

Abstract

LCTMF is radio-responsive, with EQD2 >12.0 Gy associated with 100 % ORR. Dose-response was observed, with EQD2 >36.0 Gy achieving 100 % CR rate. For unifocal cutaneous LCTMF, RT-alone achieved excellent infield control with possible curative potential in a proportion of patients.

Radiotherapy and OncologyVol. 215
The Royal Melbourne Hospital (AU), Peter MacCallum Cancer Centre (AU)
Openalex Percentile: Top 42%
Cutaneous lymphoproliferative disorders research
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