Association of LAMA3 expression with perineural invasion and chemoresistance in pancreatic ductal adenocarcinoma
LAMA3 expression level is an independent risk factor for the occurrence of neuroinvasion in PDAC patients; LAMA3 expression level, TNM staging and prognosis of PDAC patients are correlated; LAMA3 expression level may serve as a valuable biomarker for the occurrence, development, and prediction of prognosis of patients with PDAC, and also as a potential therapeutic target for PDAC patients.
Authors
- Xiaohong Wang (ORCID: https://orcid.org/0000-0003-1367-9334)
- Yeben Qian (ORCID: https://orcid.org/0000-0003-2061-423X)
- Yang Yang (ORCID: https://orcid.org/0000-0002-1163-2359)
- Yongqiang Chen (ORCID: https://orcid.org/0000-0003-3395-8023)
- Qikai Sun (ORCID: https://orcid.org/0000-0001-6704-9843)
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1007/s12672-025-03971-5
- Primary Topic
- Cell Adhesion Molecules Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00