Defining Optimal Residual Tumor Volume for Survival in IDH-Wildtype Glioblastoma
An RTV of 1.75 cm<sup>3</sup> confers optimal survival benefit in IDH wildtype GBM. A threshold RTV of 1.75 cm<sup>3</sup> in methylated and 2.50 cm<sup>3</sup> in unmethylated IDH wildtype GBM confers optimal survival benefit. Our findings suggest that RTV may be a more accurate prognostic tool than EOR and could guide surgical decision-making.
Authors
- Chien Yew Kow (ORCID: https://orcid.org/0000-0002-3897-8368)
- Lawrence Choi
- Angela Mweempwa (ORCID: https://orcid.org/0000-0001-8231-7746)
- A. Falkov
- John F. Sheridan (ORCID: https://orcid.org/0000-0002-6927-0266)
- Hugh McHugh (ORCID: https://orcid.org/0000-0002-5323-9926)
- Jason Correia
- J Antony
- Shayan Moosa
- Luis Slyfield
- Simran Chandhok
Institutions
- Auckland City Hospital (NZ)
Publication Details
- Journal
- World Neurosurgery
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.wneu.2025.124642
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00