APOBEC3B/ASF1B–TGF-β signaling axis promotes epithelial–mesenchymal transition in HPV-positive oropharyngeal cancer
These findings identify APOBEC3B/ASF1B as a central pathway through which HPV infection activates TGF-β signaling and promotes EMT, offering potential biomarkers and therapeutic targets for high-risk HPV-positive OPC.
Authors
- Chi‐Tai Yeh (ORCID: https://orcid.org/0000-0001-5189-9755)
- Ming‐Shou Hsieh
- Yang‐Che Wu (ORCID: https://orcid.org/0000-0003-3058-832X)
- Tung-Nien Hsu
- Wei‐Jen Chang (ORCID: https://orcid.org/0000-0003-1160-2130)
- Chih-Chi Sheen
Institutions
- National Taitung University (TW)
- Taipei Medical University-Shuang Ho Hospital (TW)
- Taipei Medical University (TW)
Publication Details
- Journal
- Journal of Dental Sciences
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.jds.2025.10.039
- Primary Topic
- TGF-β signaling in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00