Osteochondral knee joint lesion treated with an aragonite-based scaffold. 12-year follow-up of the world's first implantation: Case report
Articular surface lesions, which include chondral and osteochondral defects, are debilitating and favor the development of osteoarthritis. The long-term follow-up of the world's first case of implantation of an aragonite-based scaffold (Agili-C™, from CartiHeal) in a chronic post-traumatic osteochondral knee joint lesion (International Cartilage Repair Society (ICRS) grade IV, size 2 cm<sup>2</sup>) was presented. Over a decade after implantation, the treatment results remained stable, the patient was fully satisfied, and was able to resume his preinjury activities. Despite the partial meniscectomy of the medial meniscus, the degenerative process was successfully contained, with only subtle osteophytes and mild narrowing of the medial compartment. In addition, radiologic monitoring of the restored bone and cartilage tissue showed successful and durable results. STUDY DESIGN: Case-report (level of evidence: V).
Authors
- Elizaveta Kon (ORCID: https://orcid.org/0000-0003-0649-2336)
- Matej Drobnič (ORCID: https://orcid.org/0000-0002-3770-5990)
- Matic Kolar (ORCID: https://orcid.org/0000-0003-0197-2744)
- Dror Robinson (ORCID: https://orcid.org/0000-0003-2517-4069)
- Nir Altschuler
Institutions
- Humanitas University (IT)
- Rabin Medical Center (IL)
- Ljubljana University Medical Centre (SI)
- Lev Hasharon Hospital (IL)
- IRCCS Humanitas Research Hospital (IT)
Publication Details
- Journal
- Journal of ISAKOS Joint Disorders & Orthopaedic Sports Medicine
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.jisako.2025.101040
- Primary Topic
- Knee injuries and reconstruction techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00