Comparative Ultrasonic Bath and Probe Extraction of Piperine from Piper nigrum L. Using Natural Deep Eutectic Solvents: RSM Optimization, Characterization, and In Vitro Bioactivity
These findings indicate that UPE using NADES is a sustainable approach for high-yield piperine extraction with enhanced purity and bioactivity, supporting its potential for pharmaceutical applications.
Authors
- Beryl Vedha Yesudhason (ORCID: https://orcid.org/0000-0002-9262-8959)
- Maharshi Bhaswant (ORCID: https://orcid.org/0000-0003-4501-5487)
- Johnson Retnaraj Samuel Selvan Christyraj (ORCID: https://orcid.org/0000-0001-7662-8150)
- Yolin Angel Poomany Arul Soundara Rajan (ORCID: https://orcid.org/0000-0001-8173-9648)
- Abdullah Mohammed Ayedh Al Adhreai
Institutions
- National Institute of Technology Tiruchirappalli (IN)
- Indian Institute of Management Tiruchirappalli (IN)
- Sathyabama Institute of Science and Technology (IN)
Publication Details
- Journal
- Biomolecules
- Published
- 2025-11-20
- DOI
- https://doi.org/10.3390/biom15111631
- Primary Topic
- Piperaceae Chemical and Biological Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00