Altered gut microbial functional pathways in people with irritable bowel syndrome enable precision health insights

Rather than waiting to diagnose IBS after symptoms appear, these functional pathway scores can help to provide early health insights into molecular pathways that may contribute to IBS. These molecular endpoints could also assist with measuring the efficacy of practical interventions, developing related algorithms, providing personalized nutritional recommendations, diagnostic support, and treatments for gastrointestinal disorders like IBS.

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Publication Details

Journal
BMC Gastroenterology
Published
2025-11-20
DOI
https://doi.org/10.1186/s12876-025-04205-2
Primary Topic
Gastrointestinal motility and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Altered gut microbial functional pathways in people with irritable bowel syndrome enable precision health insights

Eric Patridge, Oyetunji Ogundijo, Guruduth Banavar, Lan Hu et al.
BMC Gastroenterology
Gastrointestinal motility and disorders
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Altered gut microbial functional pathways in people with irritable bowel syndrome enable precision health insights

Eric Patridge, Oyetunji Ogundijo, Guruduth Banavar, Lan Hu, Matthew M. Molusky, Momchilo Vuyisich, Anmol Gorakshakar, Grant Antoine, Cristina Julian, Robert Wohlman
article en

Abstract

Rather than waiting to diagnose IBS after symptoms appear, these functional pathway scores can help to provide early health insights into molecular pathways that may contribute to IBS. These molecular endpoints could also assist with measuring the efficacy of practical interventions, developing related algorithms, providing personalized nutritional recommendations, diagnostic support, and treatments for gastrointestinal disorders like IBS.

BMC GastroenterologyVol. 25(1)
VinTech (United States) (US)
Openalex Percentile: Top 50%
Gastrointestinal motility and disorders
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