Selective vulnerability of GABAergic neurons in chronic migraine

These findings reveal a male-specific vulnerability of GABAergic neurons in chronic migraine and suggest a sex-dependent divergence in the underlying pathophysiological mechanisms. This highlights the critical need for sex-specific approaches to migraine research and therapeutic development.

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Publication Details

Journal
The Journal of Headache and Pain
Published
2025-11-20
DOI
https://doi.org/10.1186/s10194-025-02223-9
Primary Topic
Migraine and Headache Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Selective vulnerability of GABAergic neurons in chronic migraine

Anju Vasudevan, Yibu Chen, Chenchen Xia, Xianghong Arakaki et al.
The Journal of Headache and Pain
Migraine and Headache Studies
article

Selective vulnerability of GABAergic neurons in chronic migraine

Anju Vasudevan, Yibu Chen, Chenchen Xia, Xianghong Arakaki, Kazi Helal Hossain, Meng Li, Justin Lin, Emily Abad, Timothy Chuong
article en

Abstract

These findings reveal a male-specific vulnerability of GABAergic neurons in chronic migraine and suggest a sex-dependent divergence in the underlying pathophysiological mechanisms. This highlights the critical need for sex-specific approaches to migraine research and therapeutic development.

The Journal of Headache and PainVol. 26(1)
University of Southern California (US), Huntington Medical Research Institutes (US), LAC+USC Medical Center (US)
Openalex Percentile: Top 58%
Migraine and Headache Studies
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