Peptidyl-prolyl isomerase A promotes migration and invasion of hepatoma cells by regulating Nrf2 and inhibiting ferroptosis

This study highlights the potential role of PPIA as a critical oncogenic driver in liver cancer, suggesting that targeting PPIA could offer therapeutic advantages in the treatment of this malignancy.

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Publication Details

Journal
Minerva Gastroenterology
Published
2025-11-20
DOI
https://doi.org/10.23736/s2724-5985.25.03964-6
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Peptidyl-prolyl isomerase A promotes migration and invasion of hepatoma cells by regulating Nrf2 and inhibiting ferroptosis

Pengbo Zhang, Xuning Wang, Jiankun Zhang
Minerva Gastroenterology
Ferroptosis and cancer prognosis
article

Peptidyl-prolyl isomerase A promotes migration and invasion of hepatoma cells by regulating Nrf2 and inhibiting ferroptosis

Pengbo Zhang, Xuning Wang, Jiankun Zhang
article en

Abstract

This study highlights the potential role of PPIA as a critical oncogenic driver in liver cancer, suggesting that targeting PPIA could offer therapeutic advantages in the treatment of this malignancy.

Minerva GastroenterologyVol. 72(1)
Yantaishan Hospital (CN), The First People's Hospital of Zhaoqing (CN)
Openalex Percentile: Top 49%
Ferroptosis and cancer prognosis
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