Polygenic Risk Score as a Predictor of Bone Fracture or Osteoporosis in Prostate Cancer Patients Receiving Androgen Deprivation Therapy
This hospital-based cohort study among Han Chinese highlights PRS as a potential biomarker for bone fracture and osteoporosis risk in prostate cancer patients initiating ADT. It provides a basis for personalized risk assessment and early intervention with bone protective strategies.
Authors
- Li‐Wen Chang (ORCID: https://orcid.org/0000-0001-9764-6278)
- Jian‐Ri Li (ORCID: https://orcid.org/0000-0002-4626-9369)
- Y. Liu (ORCID: https://orcid.org/0009-0003-0621-2725)
- I‐Chieh Chen (ORCID: https://orcid.org/0000-0002-8345-5304)
- Yi‐Ming Chen (ORCID: https://orcid.org/0000-0001-7593-3065)
- Sheng‐Chun Hung
- Huiwen Yang (ORCID: https://orcid.org/0009-0003-5768-8424)
Institutions
- National Chung Hsing University (TW)
- Taichung Veterans General Hospital (TW)
- Chung Shan Medical University (TW)
- Hungkuang University (TW)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1002/cam4.71395
- Citations
- 1
- Primary Topic
- Bone health and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.05