Presence of acrylamide in key food sources within the European Mediterranean framework

Acrylamide (AA) is a low-molecular-weight compound formed primarily through the Maillard reaction in carbohydrate-rich, low-protein foods subjected to high temperatures under low-moisture conditions. Since its classification as a "probable human carcinogen", AA has attracted substantial scientific attention. Although non-dietary sources of AA exposure exist, dietary intake remains the predominant route, accounting for approximately 38 % of total caloric consumption from foods potentially containing this compound. In Europe, the principal dietary sources of AA have been identified as fried potato products, coffee, and crackers. To assess dietary AA exposure within the European Mediterranean framework, 85 food samples were collected across Spain and Italy. Measured AA content exhibited considerable variability, ranging from 30 to 1905 μg kg<sup>-1</sup>. Based on these findings, dietary exposure estimated and associated health risks were calculated. The Estimated Daily Intakes (EDIs) represented to approximately 20-28 % of the lowest EDI value reported by the European Food Safety Authority (EFSA) for the European population (0.4 μg·kg-bw<sup>-1</sup>·day<sup>-1</sup>), highlighting their potential relevance. Risk assessment outcomes suggest that dietary AA exposure may pose a health concern. Consequently, periodic monitoring and surveillance of AA levels in food products including the assessment of its dietary exposure are essential to protect public health.

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Journal
Food and Chemical Toxicology
Published
2025-11-20
DOI
https://doi.org/10.1016/j.fct.2025.115856
Primary Topic
Potato Plant Research
Type
article
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article

Presence of acrylamide in key food sources within the European Mediterranean framework

Clara Coscollà, Giuseppa Di Bella, Olga Pardo, Vincenzo Nava et al.
Food and Chemical Toxicology
Potato Plant Research
article

Presence of acrylamide in key food sources within the European Mediterranean framework

Clara Coscollà, Giuseppa Di Bella, Olga Pardo, Vincenzo Nava, Borja Peris-Camarasa, Cristina Aleixandre
article en

Abstract

Acrylamide (AA) is a low-molecular-weight compound formed primarily through the Maillard reaction in carbohydrate-rich, low-protein foods subjected to high temperatures under low-moisture conditions. Since its classification as a "probable human carcinogen", AA has attracted substantial scientific attention. Although non-dietary sources of AA exposure exist, dietary intake remains the predominant route, accounting for approximately 38 % of total caloric consumption from foods potentially containing this compound. In Europe, the principal dietary sources of AA have been identified as fried potato products, coffee, and crackers. To assess dietary AA exposure within the European Mediterranean framework, 85 food samples were collected across Spain and Italy. Measured AA content exhibited considerable variability, ranging from 30 to 1905 μg kg<sup>-1</sup>. Based on these findings, dietary exposure estimated and associated health risks were calculated. The Estimated Daily Intakes (EDIs) represented to approximately 20-28 % of the lowest EDI value reported by the European Food Safety Authority (EFSA) for the European population (0.4 μg·kg-bw<sup>-1</sup>·day<sup>-1</sup>), highlighting their potential relevance. Risk assessment outcomes suggest that dietary AA exposure may pose a health concern. Consequently, periodic monitoring and surveillance of AA levels in food products including the assessment of its dietary exposure are essential to protect public health.

Food and Chemical ToxicologyVol. 207
University of Messina (IT), Universitat de València (ES), Generalitat Valenciana (ES), Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (ES)
Openalex Percentile: Top 59%
Potato Plant Research
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Presence of acrylamide in key food sources within the European Mediterranean framework — Clara Coscollà, Giuseppa Di Bella, et al. · Food and Chemical Toxicology (2025) | TGRS Research Map | TGRS