Oncotype Dx Breast Cancer Assay in Older Patients: A Real Life Cohort

This observational study highlights that the Oncotype DX test supports therapeutic de-escalation in patients with RS ≤ 25 and serves as a prognostic marker. Oncogeriatric evaluations are essential to guide adjuvant treatments in older breast cancer patients prior to using genomic signatures.

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Publication Details

Journal
Cancer Medicine
Published
2025-11-01
DOI
https://doi.org/10.1002/cam4.71386
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Oncotype Dx Breast Cancer Assay in Older Patients: A Real Life Cohort

Jean‐Pierre Lotz, Coralie Prebet, Marc‐Antoine Benderra, Anne Sabaila et al.
Cancer Medicine
Breast Cancer Treatment Studies
article

Oncotype Dx Breast Cancer Assay in Older Patients: A Real Life Cohort

Jean‐Pierre Lotz, Coralie Prebet, Marc‐Antoine Benderra, Anne Sabaila, Mathieu Jamelot, Marjolaine Le Gac, Joseph Gligorov, Djamel Ghebriou, David Buob, Mariana Nedelcu, Lauren Seknazi, Clément Grosnon
article en

Abstract

This observational study highlights that the Oncotype DX test supports therapeutic de-escalation in patients with RS ≤ 25 and serves as a prognostic marker. Oncogeriatric evaluations are essential to guide adjuvant treatments in older breast cancer patients prior to using genomic signatures.

Cancer MedicineVol. 14(22)
Sorbonne Université (FR), Hôpital Tenon (FR)
Openalex Percentile: Top 57%
Breast Cancer Treatment Studies
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