Carbapenem-Induced Platelet Abnormalities: A Systematic Review Literature Analysis of Platelet Abnormality Caused by Carbapenems

Carbapenem-induced platelet abnormalities appear to be more frequent than previously recognized, predominantly occurring within the first week of therapy. This potentially severe adverse drug reaction should be particularly considered in elderly patients receiving meropenem therapy.

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Publication Details

Journal
Infection and Drug Resistance
Published
2025-11-01
DOI
https://doi.org/10.2147/idr.s555737
Primary Topic
Antibiotics Pharmacokinetics and Efficacy
Type
article
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0.00
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article

Carbapenem-Induced Platelet Abnormalities: A Systematic Review Literature Analysis of Platelet Abnormality Caused by Carbapenems

Zhenxing Li, Chao Ye, Wei Peng, Xu Zhang et al.
Infection and Drug Resistance
Antibiotics Pharmacokinetics and Efficacy
article

Carbapenem-Induced Platelet Abnormalities: A Systematic Review Literature Analysis of Platelet Abnormality Caused by Carbapenems

Zhenxing Li, Chao Ye, Wei Peng, Xu Zhang, Xiaojuan Zhang, Minghui Wu, Lingzhi Zhou, Qiongliang Yang, Juan Pan
article en

Abstract

Carbapenem-induced platelet abnormalities appear to be more frequent than previously recognized, predominantly occurring within the first week of therapy. This potentially severe adverse drug reaction should be particularly considered in elderly patients receiving meropenem therapy.

Infection and Drug ResistanceVol. Volume 18
Hunan University of Traditional Chinese Medicine (CN), Guangdong Provincial Hospital of Traditional Chinese Medicine (CN), Hunan Academy of Traditional Chinese Medicine (CN), Liuyang City Maternal and Child Health Hospital (CN), Hunan Provincial People's Hospital (CN)
Openalex Percentile: Top 61%
Antibiotics Pharmacokinetics and Efficacy
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