Protein-losing enteropathy following Fontan completion: A 30-year national cohort study in Sweden
PLE remains a serious complication following Fontan, with notable mortality. Patients with right ventricular morphology of the systemic ventricle had a higher risk of PLE. Previous pulmonary venous congestion was common when PLE was diagnosed early after Fontan. Catheter-based interventions were frequently used to optimize hemodynamics; lymphatic interventions are likely to become more common. In therapy-refractory patients, heart transplantation remains an option.
Authors
- Erik Herou (ORCID: https://orcid.org/0000-0002-8071-0381)
- Karin Tran‐Lundmark (ORCID: https://orcid.org/0000-0001-5973-2618)
- Jan Sunnegårdh (ORCID: https://orcid.org/0000-0002-8280-2693)
- Indra Schütz
- Gunnar Bergman (ORCID: https://orcid.org/0000-0003-1619-0171)
- Felicia Nordenstam (ORCID: https://orcid.org/0000-0001-7549-690X)
- Annika Rydberg (ORCID: https://orcid.org/0000-0001-9655-7783)
- Petru Liuba
- Kiet A. Tran (ORCID: https://orcid.org/0000-0002-8388-2912)
- Mikaela Dolk (ORCID: https://orcid.org/0009-0009-3916-7864)
- Mats Synnergren (ORCID: https://orcid.org/0009-0000-1534-6862)
- Katarina Hanséus (ORCID: https://orcid.org/0000-0002-7464-0444)
Institutions
- Karolinska University Hospital (SE)
- Lund University (SE)
- Sahlgrenska University Hospital (SE)
- Karolinska Institutet (SE)
- Skåne University Hospital (SE)
- Umeå University (SE)
Publication Details
- Journal
- Journal of Thoracic and Cardiovascular Surgery
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.jtcvs.2025.11.008
- Primary Topic
- Congenital Heart Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hjärt-Lungfonden
- Knut och Alice Wallenbergs Stiftelse
- Vetenskapsrådet