Hemocompatibility Outcomes With Pharmacological Therapy Following LVAD Implantation
Background pharmacologic therapy did not modify the effect of aspirin on HRAE; however, the use of a RAAS inhibitor was independently associated with a reduction in HRAE. These exploratory observations may potentially point to opportunity for enhancing hemocompatibility in patients receiving LVAD therapy. (Antiplatelet Removal and Hemocompatibility Events With the HeartMate 3 Pump [ARIES-HM3]; NCT04069156).
Authors
- Pavan Atluri (ORCID: https://orcid.org/0000-0003-0229-085X)
- Finn Gustafsson (ORCID: https://orcid.org/0000-0003-2144-341X)
- F. Lee
- Nir Y. Uriel (ORCID: https://orcid.org/0000-0003-2301-3587)
- Ulrich P. Jorde (ORCID: https://orcid.org/0000-0002-9476-6466)
- David D'Allesandro
- Craig H. Selzman (ORCID: https://orcid.org/0000-0001-9218-4764)
- Mary Keebler (ORCID: https://orcid.org/0000-0002-9797-6995)
- Anelechi Anyanwu
- Francis D. Pagani (ORCID: https://orcid.org/0000-0003-4430-9969)
- Jason N. Katz (ORCID: https://orcid.org/0000-0002-3460-5169)
- Mandeep R. Mehra (ORCID: https://orcid.org/0000-0001-8683-7044)
- Jean M. Connors (ORCID: https://orcid.org/0000-0001-6445-582X)
- Ivan Netuka (ORCID: https://orcid.org/0000-0002-1567-7036)
- Nasir Sulemanjee (ORCID: https://orcid.org/0000-0001-6715-4221)
- Jeffrey D. Alexis (ORCID: https://orcid.org/0000-0002-1599-0487)
- Mirnela Byku (ORCID: https://orcid.org/0000-0002-4541-5053)
- Sriram Nathan
- Scott P. Porter (ORCID: https://orcid.org/0000-0002-1017-5010)
Institutions
- University of North Carolina at Chapel Hill (US)
- Brigham and Women's Hospital (US)
- Albert Einstein College of Medicine (US)
- Montefiore Medical Center (US)
- NewYork–Presbyterian Hospital (US)
- Harvard University (US)
- University of Utah (US)
- University of Michigan (US)
- Columbia University Irving Medical Center (US)
- Massachusetts General Hospital (US)
- Abbott (United States) (US)
- Bellevue Hospital Center (US)
- Aurora St. Luke's Medical Center (US)
- Institute of Clinical and Experimental Medicine (CZ)
- University of Pittsburgh Medical Center (US)
- The University of Texas Health Science Center (US)
- University of Rochester (US)
- University of Pennsylvania (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- JACC Heart Failure
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.jchf.2025.102769
- Citations
- 1
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 0.67