Clinical Outcomes of Methadone for Refractory Cancer Pain, Including Add-On Switching to Prior Opioids.

Methadone proved effective for refractory cancer pain, particularly using the add-on method, which tend to be equally safe and effective as well as the SAG approach. The add-on method's flexibility in maintaining prior opioid regimens may support its use in clinical practice.

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Journal
PubMed
Published
2025-11-01
Primary Topic
Pain Management and Opioid Use
Type
article
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article

Clinical Outcomes of Methadone for Refractory Cancer Pain, Including Add-On Switching to Prior Opioids.

Takashi Kawakubo, S. Kikuta, Kyoko Ueda, Yuko Shiota et al.
PubMed
Pain Management and Opioid Use
article

Clinical Outcomes of Methadone for Refractory Cancer Pain, Including Add-On Switching to Prior Opioids.

Takashi Kawakubo, S. Kikuta, Kyoko Ueda, Yuko Shiota, Nami Suda, Yuta Miyazawa, Shingo Yano, Yutaro Kamiyama, Aya Nakano
article en

Abstract

Methadone proved effective for refractory cancer pain, particularly using the add-on method, which tend to be equally safe and effective as well as the SAG approach. The add-on method's flexibility in maintaining prior opioid regimens may support its use in clinical practice.

PubMedVol. 52(11)
The Jikei University Hospital (JP)
Openalex Percentile: Top 47%
Pain Management and Opioid Use
OpenAlex
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Clinical Outcomes of Methadone for Refractory Cancer Pain, Including Add-On Switching to Prior Opioids. — Takashi Kawakubo, S. Kikuta, et al. · PubMed (2025) | TGRS Research Map | TGRS