Identification and validation of mitochondrial and programmed cell death-related prognostic markers in pediatric acute myeloid leukemia
PDHA1, OGG1, and OPA1 were identified as potential prognostic markers for pediatric AML, providing valuable insights for the development of targeted therapeutic strategies. However, further validation in larger and more diverse clinical cohorts is still required to confirm its clinical applicability.
Authors
- Yonghuan Li
- Bei Liu (ORCID: https://orcid.org/0000-0003-4331-2138)
- Qiang Zhao (ORCID: https://orcid.org/0000-0003-4881-1104)
- Xiaoyan Hu
- Wei Deng
Institutions
- Gansu Provincial Maternal and Child Health Hospital (CN)
- First Hospital of Lanzhou University (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.3389/fimmu.2025.1671230
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00