Clinical Utility of Serum Neurofilament Light Chain in Peripheral Neuropathy

Routine sNfL testing is warranted in selected patients with PN, such as treatment-naïve or refractory CIDP, active vasculitic PN, and ATTRv-PN. Elevated sNfL in patients with PN should prompt evaluation for a potentially treatable cause and may offer useful adjunctive information to support clinical decision-making.

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Publication Details

Journal
Muscle & Nerve
Published
2025-11-20
DOI
https://doi.org/10.1002/mus.70073
Primary Topic
Peripheral Neuropathies and Disorders
Type
article
Field-Weighted Citation Impact
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article

Clinical Utility of Serum Neurofilament Light Chain in Peripheral Neuropathy

Chafic Karam
Muscle & Nerve
Peripheral Neuropathies and Disorders
article

Clinical Utility of Serum Neurofilament Light Chain in Peripheral Neuropathy

Chafic Karam
article en

Abstract

Routine sNfL testing is warranted in selected patients with PN, such as treatment-naïve or refractory CIDP, active vasculitic PN, and ATTRv-PN. Elevated sNfL in patients with PN should prompt evaluation for a potentially treatable cause and may offer useful adjunctive information to support clinical decision-making.

Muscle & NerveVol. 73(1)
University of Pennsylvania (US)
Openalex Percentile: Top 51%
Peripheral Neuropathies and Disorders
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Clinical Utility of Serum Neurofilament Light Chain in Peripheral Neuropathy — Chafic Karam · Muscle & Nerve (2025) | TGRS Research Map | TGRS