Season-dependent low basal CD86 expression promotes immune cell activation upon treatment with plasma-derived factor Ⅷ products
In fact, we could demonstrate that the meteorological season correlates with the basal CD86 expression on DC. This, in turn, determined the capability of synergistic DC activation and cytokine secretion, as well as partially impacted T-cell proliferation.
Authors
- Stefanie Kronhart
- Gerrit J. K. Praefcke (ORCID: https://orcid.org/0000-0001-8818-1499)
- Martina Anzaghe (ORCID: https://orcid.org/0000-0002-7983-3835)
- Jessica Herzig
- Eva Ringler
- Zoe Waibler (ORCID: https://orcid.org/0000-0001-5758-2652)
- S. Küster
- Jennifer Martinez (ORCID: https://orcid.org/0000-0002-3060-2518)
- Lilija Miller
Institutions
- Paul Ehrlich Institut (DE)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.rpth.2025.103256
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 0.00