Ciprofol versus propofol for sedation in colonoscopy: a systematic review and meta-analysis of randomized controlled trials
Ciprofol provides comparable efficacy to propofol for colonoscopy sedation, with a lower incidence of respiratory depression, injection pain, and hypotension. Patient satisfaction was slightly higher with ciprofol, while bradycardia occurrence was similar. These findings suggest ciprofol as a promising alternative, though further large-scale studies are needed to confirm its clinical benefits.
Authors
- Plínio da Cunha Leal (ORCID: https://orcid.org/0000-0003-1336-8528)
- Caio Márcio Barros de Oliveira (ORCID: https://orcid.org/0000-0002-5068-9067)
- Saul Dominici (ORCID: https://orcid.org/0009-0009-3269-635X)
- A. Santos (ORCID: https://orcid.org/0000-0002-1347-2598)
- Italo C. Martins (ORCID: https://orcid.org/0009-0000-5689-9236)
- B. Ribeiro
- Victor Arthur Ohannesian (ORCID: https://orcid.org/0009-0007-8742-1818)
- Brunno Braga Sauaia
Institutions
- Hospital Israelita Albert Einstein (BR)
- Hospital São Paulo (BR)
- Universidade Federal do Maranhão (BR)
Publication Details
- Journal
- Brazilian Journal of Anesthesiology (English Edition)
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.bjane.2025.844710
- Citations
- 1
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 2.19