Prevalence and correlates of PrEP use and missed PrEP doses due to alcohol among sexually active adults and sexual minority men in San Francisco

PrEP prevalence is low, with more than half the participants reporting missed PrEP doses due to alcohol use, which was associated with engaging in sexual activity while under the influence of alcohol. Furthermore, PrEP use is associated with increased alcohol use and recent STIs diagnoses. These findings can help optimize interventions to increase PrEP use and adherence among sexually active adults who drink alcohol, including SMM. Further, the findings also highlight the need for integrating alcohol use interventions into PrEP care.