Reversal of fentanyl-induced laryngospasm with ketanserin and naloxone: A prospective randomized blinded study in rats
Co-administration of ketanserin and naloxone resolved fentanyl-induced laryngospasm with an enhanced glottic opening compared to baseline. Findings suggest that both opioid and serotonergic mechanisms can be involved in fentanyl-induced laryngospasm.
Authors
- Inger Lise Bogen (ORCID: https://orcid.org/0000-0003-2877-0624)
- Andreas Lervik
- Jannike Mørch Andersen (ORCID: https://orcid.org/0000-0002-8425-9743)
- Janicke Nordgreen
- Emma Pettersson (ORCID: https://orcid.org/0000-0002-4776-9162)
- Nora Digranes (ORCID: https://orcid.org/0009-0001-6692-8309)
- Henning Andreas Haga
Institutions
- Oslo University Hospital (NO)
- Lovisenberg Diakonale Høgskole (NO)
- Norwegian University of Life Sciences (NO)
Publication Details
- Journal
- Drug and Alcohol Dependence
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.drugalcdep.2025.112969
- Primary Topic
- Respiratory and Cough-Related Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00