Predicting Outcomes of Early and Late Acute Periprosthetic Joint Infections Treated With Debridement, Irrigation, and Implant Retention: An External Validation of the CRIME80 (COPD, C-Reactive Protein, Rheumatoid Arthritis, Index Surgery, Male, Excha
Our study found that the CRIME80 tool had limited predictive performance. This finding was consistent across patients who had PJI of the hip or knee and early or late acute infection. Given these findings, the benefit of implementing the CRIME80 score in clinical practice remains uncertain.
Authors
- Sharmala Thuraisingam (ORCID: https://orcid.org/0000-0002-9450-1302)
- Craig Aboltins (ORCID: https://orcid.org/0000-0002-7578-882X)
- Àlex Soriano (ORCID: https://orcid.org/0000-0002-9374-0811)
- Michelle M. Dowsey (ORCID: https://orcid.org/0000-0002-9708-5308)
- Elise Naufal
- Simon W. Young (ORCID: https://orcid.org/0000-0002-0286-8052)
- Sina Babazadeh (ORCID: https://orcid.org/0000-0003-2151-0950)
- Cade Shadbolt (ORCID: https://orcid.org/0000-0002-0937-2412)
- Peter Choong (ORCID: https://orcid.org/0000-0002-3522-7374)
- Jesse E. Otero (ORCID: https://orcid.org/0000-0003-2142-6863)
- Nicolas Santiago Piuzzi (ORCID: https://orcid.org/0000-0003-3007-7538)
- Marjan Wouthuyzen‐Bakker (ORCID: https://orcid.org/0000-0001-7866-2467)
- Yale A. Fillingham (ORCID: https://orcid.org/0000-0002-6626-9913)
- Carlos A. Higuera
Institutions
- Cleveland Clinic (US)
- University Medical Center Groningen (NL)
- Thomas Jefferson University (US)
- University of Groningen (NL)
- North Shore Hospital (NZ)
- St Vincent's Hospital Melbourne (AU)
- Rothman Orthopaedics (US)
- Cleveland Clinic Florida (US)
- Hospital Clínic de Barcelona (ES)
- OrthoCarolina (US)
- Rothman Institute (US)
Publication Details
- Journal
- The Journal of Arthroplasty
- Published
- 2025-11-01
- DOI
- https://doi.org/10.1016/j.arth.2025.11.021
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Australian Government