Corneal nerve loss measured by corneal confocal microscopy predicts pain severity in Parkinson's disease
Corneal nerve degeneration is significantly associated with pain in PD and may serve as an independent biomarker. SFN likely contributes to peripheral pain mechanisms in PD, involving complex peripheral and central interactions.
Authors
- Min Xu (ORCID: https://orcid.org/0000-0003-1558-4283)
- Kun Zan (ORCID: https://orcid.org/0009-0007-7985-4912)
- Chuanying Xu (ORCID: https://orcid.org/0009-0006-0851-9298)
- Guiyun Cui (ORCID: https://orcid.org/0000-0001-9675-8497)
- Zixuan Zhang
- Jinyu Li (ORCID: https://orcid.org/0000-0001-6799-0182)
- Xi Wang (ORCID: https://orcid.org/0009-0004-9115-8539)
- Yuning Liu (ORCID: https://orcid.org/0000-0002-0513-4011)
- Liying Yang (ORCID: https://orcid.org/0000-0001-6833-8540)
- Zihao Lin
- Peixiao Yin (ORCID: https://orcid.org/0009-0008-8521-0408)
- Chenyang Guan
- Xuebin Niu
Institutions
- Xuzhou Medical College (CN)
- Second Hospital of Shandong University (CN)
Publication Details
- Journal
- Neurobiology of Disease
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.nbd.2025.107197
- Citations
- 1
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 1.88