GLP-1 Receptor Agonists as Treatment of Nondiabetic Ischemic Stroke: A Systematic Review and Meta-Analysis

GLP-1 RA improves functional outcome and reduces infarct volume in preclinical animal stroke models without diabetes. Translating these promising preclinical findings into clinical benefits remains a key challenge and a critical opportunity for future research.

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Publication Details

Journal
Stroke
Published
2025-11-20
DOI
https://doi.org/10.1161/strokeaha.125.053075
Citations
2
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
2.59
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article

GLP-1 Receptor Agonists as Treatment of Nondiabetic Ischemic Stroke: A Systematic Review and Meta-Analysis

Jan Brink Valentin, Christina Kruuse, Julie Brogaard Larsen, Mads Svart et al.
2 citations
Stroke
Diabetes Treatment and Management
2.59
article

GLP-1 Receptor Agonists as Treatment of Nondiabetic Ischemic Stroke: A Systematic Review and Meta-Analysis

Jan Brink Valentin, Christina Kruuse, Julie Brogaard Larsen, Mads Svart, Rolf Ankerlund Blauenfeldt, Kim Ryun Drasbek, Claus Z. Simonsen, Michael K. Michaelsen
article en
2 citations

Abstract

GLP-1 RA improves functional outcome and reduces infarct volume in preclinical animal stroke models without diabetes. Translating these promising preclinical findings into clinical benefits remains a key challenge and a critical opportunity for future research.

StrokeVol. 57(2)
Steno Diabetes Centers (DK), Aarhus University (DK), Aarhus University Hospital (DK), Copenhagen University Hospital (DK), University College Copenhagen (DK), Regional Hospital Horsens (DK), Aalborg University (DK)
Openalex Percentile: Top 8%
Diabetes Treatment and Management
2.59
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GLP-1 Receptor Agonists as Treatment of Nondiabetic Ischemic Stroke: A Systematic Review and Meta-Analysis — Jan Brink Valentin, Christina Kruuse, et al. · Stroke (2025) | TGRS Research Map | TGRS