Endothelial Cells Differentiated from Human Induced Pluripotent Stem Cells Form Aligned Network Structures in Engineered Neural Tissue
This work rapidly generated engineered nerve tissue containing highly aligned endothelial tube-like structures, resembling key features of the early nerve regeneration bridge. Therefore, this 3D engineered tissue provides a platform to study the effects of endothelial cell structures in nerve repair treatment and translational development.
Authors
- James B. Phillips (ORCID: https://orcid.org/0000-0001-8117-3074)
- Parmjit Jat (ORCID: https://orcid.org/0000-0002-3354-0594)
- Poppy O. Smith (ORCID: https://orcid.org/0000-0002-3325-5400)
Institutions
- Nerve Centre (GB)
- MRC Prion Unit (GB)
- University College London (GB)
Publication Details
- Journal
- Journal of Functional Biomaterials
- Published
- 2025-11-20
- DOI
- https://doi.org/10.3390/jfb16110425
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 0.00