Haemostatic changes following ECMO circuit replacement in adult patients with COVID-19: An exploratory retrospective study
ECMO circuit exchanges are associated with significant improvements in coagulation parameters, particularly d-dimer reduction, suggesting that d-dimer trends may serve as a key indicator for elective circuit replacement. Future prospective studies should refine exchange criteria to optimize patient outcomes while minimizing unnecessary interventions.
Authors
- Alexander Hermann (ORCID: https://orcid.org/0000-0001-6103-7884)
- Stefan Thurner (ORCID: https://orcid.org/0000-0003-2495-6819)
- Oliver Robak
- Nina Buchtele (ORCID: https://orcid.org/0000-0002-1270-6452)
- Thomas Staudinger (ORCID: https://orcid.org/0000-0003-4311-4473)
- Bernhard Nagler
- Peter Schellongowski
Institutions
- Medical University of Vienna (AT)
Publication Details
- Journal
- Thrombosis Research
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.thromres.2025.109542
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- CSL Behring
- Universität Wien
- Medizinische Universität Wien