Design of a Reconfigurable Microfluidic System Enabled by Magnetic Miniature Robots

Microfluidics permits fluid operations at the microscale. Conventional microfluidic devices have fixed structural configurations, which restrict their adaptability for different applications. A new approach is proposed by integrating magnetic miniature robotic systems into microfluidic platforms, thereby enabling dynamic reconfiguration of the microfluidic chip. As a demonstration, the study presents four types of magnetic miniature robots, i.e., magnetic sorting robot, magnetic variable channel robot, magnetic gyroscope robot, and magnetic rotating flow channel robot, to achieve on‐chip sorting, dynamic regulation of fluid velocity, on‐chip flow regulation, and rapid mixing and bubble manipulation. This work presents a versatile and scalable solution for reconfigurable microfluidic systems, opening new avenues for real‐time control in biological and chemical processes.

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Publication Details

Journal
Advanced Intelligent Systems
Published
2025-11-20
DOI
https://doi.org/10.1002/aisy.202500745
Primary Topic
Innovative Microfluidic and Catalytic Techniques Innovation
Type
article
Field-Weighted Citation Impact
0.00

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article

Design of a Reconfigurable Microfluidic System Enabled by Magnetic Miniature Robots

Zichen Xu, Yuanhe Chen, Qingsong Xu, Yu Sun
Advanced Intelligent Systems
Innovative Microfluidic and Catalytic Techniques Innovation
article

Design of a Reconfigurable Microfluidic System Enabled by Magnetic Miniature Robots

Zichen Xu, Yuanhe Chen, Qingsong Xu, Yu Sun
article en

Abstract

Microfluidics permits fluid operations at the microscale. Conventional microfluidic devices have fixed structural configurations, which restrict their adaptability for different applications. A new approach is proposed by integrating magnetic miniature robotic systems into microfluidic platforms, thereby enabling dynamic reconfiguration of the microfluidic chip. As a demonstration, the study presents four types of magnetic miniature robots, i.e., magnetic sorting robot, magnetic variable channel robot, magnetic gyroscope robot, and magnetic rotating flow channel robot, to achieve on‐chip sorting, dynamic regulation of fluid velocity, on‐chip flow regulation, and rapid mixing and bubble manipulation. This work presents a versatile and scalable solution for reconfigurable microfluidic systems, opening new avenues for real‐time control in biological and chemical processes.

Advanced Intelligent SystemsVol. 8(3)
University of Toronto (CA), University of Macau (MO)
United Mitochondrial Disease Foundation, National Natural Science Foundation of China, Universidade de Macau, Fundo para o Desenvolvimento das Ciências e da Tecnologia
Openalex Percentile: Top 66%
Innovative Microfluidic and Catalytic Techniques Innovation
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