Efficacy and safety of anlotinib hydrochloride combined with concurrent radiotherapy in the treatment of locally advanced cervical cancer: a single-arm, single-center, exploratory, phase II clinical study

Anlotinib combined with radiotherapy demonstrates promising efficacy and acceptable safety in LACC, with a favorable DCR. The multi-target mechanism of anlotinib may contribute to consistent efficacy across different FIGO stages, supporting its potential as a therapeutic option for LACC. Larger-scale trials are warranted to validate these findings.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-11-20
DOI
https://doi.org/10.3389/fonc.2025.1662160
Primary Topic
Lung Cancer Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and safety of anlotinib hydrochloride combined with concurrent radiotherapy in the treatment of locally advanced cervical cancer: a single-arm, single-center, exploratory, phase II clinical study

Xuezhi Chang, Ye Hong, Haiyan Zhang, Hongfei Liu et al.
Frontiers in Oncology
Lung Cancer Research Studies
article

Efficacy and safety of anlotinib hydrochloride combined with concurrent radiotherapy in the treatment of locally advanced cervical cancer: a single-arm, single-center, exploratory, phase II clinical study

Xuezhi Chang, Ye Hong, Haiyan Zhang, Hongfei Liu, Yali Jiang, Hao Yin, Shabiremu Abuduaini, Gulizhaer Wufuer
article en

Abstract

Anlotinib combined with radiotherapy demonstrates promising efficacy and acceptable safety in LACC, with a favorable DCR. The multi-target mechanism of anlotinib may contribute to consistent efficacy across different FIGO stages, supporting its potential as a therapeutic option for LACC. Larger-scale trials are warranted to validate these findings.

Frontiers in OncologyVol. 15
Yili Friendship Hospital (CN)
Openalex Percentile: Top 52%
Lung Cancer Research Studies
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