Efficacy and safety of anlotinib hydrochloride combined with concurrent radiotherapy in the treatment of locally advanced cervical cancer: a single-arm, single-center, exploratory, phase II clinical study
Anlotinib combined with radiotherapy demonstrates promising efficacy and acceptable safety in LACC, with a favorable DCR. The multi-target mechanism of anlotinib may contribute to consistent efficacy across different FIGO stages, supporting its potential as a therapeutic option for LACC. Larger-scale trials are warranted to validate these findings.
Authors
- Xuezhi Chang
- Ye Hong (ORCID: https://orcid.org/0000-0001-5800-0917)
- Haiyan Zhang (ORCID: https://orcid.org/0000-0002-8356-8333)
- Hongfei Liu (ORCID: https://orcid.org/0000-0001-7838-6028)
- Yali Jiang (ORCID: https://orcid.org/0000-0003-4786-0465)
- Hao Yin (ORCID: https://orcid.org/0009-0009-0754-811X)
- Shabiremu Abuduaini
- Gulizhaer Wufuer
Institutions
- Yili Friendship Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.3389/fonc.2025.1662160
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00