Impact of tumour proximity to organs-at-risk in adaptive MR-guided SBRT for central lung tumours and metastases
Daily oMRgRT significantly improves target coverage and OAR sparing in centrally located tumours, especially in anatomically complex regions. The adaptive approach enables clinically meaningful trade-offs between tumour coverage and OAR sparing. Further studies are needed to refine adaptation protocols based on tumour sublocation.
Authors
- Stefanie Corradini (ORCID: https://orcid.org/0000-0001-8709-7252)
- Sebastian Marschner (ORCID: https://orcid.org/0000-0002-8121-358X)
- Chukwuka Eze (ORCID: https://orcid.org/0000-0003-3779-1398)
- Jan Hofmaier (ORCID: https://orcid.org/0000-0002-7936-9753)
- Vanessa da Silva Mendes (ORCID: https://orcid.org/0000-0002-6706-8590)
- Claus Belka (ORCID: https://orcid.org/0000-0002-1287-7825)
- Helmut Weingandt
- Laura Hamm
- Nina-Sophie Schmidt-Hegemann (ORCID: https://orcid.org/0000-0002-2091-3603)
- Svenja Hering (ORCID: https://orcid.org/0000-0002-5725-9959)
- Sina Mansoorian
- Diego Kauffmann‐Guerrero (ORCID: https://orcid.org/0000-0003-1471-3290)
- Guillaume Landry (ORCID: https://orcid.org/0000-0003-1707-4068)
- A. Salameh
Institutions
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- LMU Klinikum (DE)
- München Klinik (DE)
- German Center for Lung Research (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.ctro.2025.101079
- Primary Topic
- MRI in cancer diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00