Impact of excluding internal mammary node coverage on musculoskeletal dosimetry in breast radiotherapy
This retrospective <i>in silico</i> dosmetric analysis clearly demonstrated that excluding IMN coverage for breast RT significantly reduced the dose received by the MSK structures of the neck, chest wall, and shoulder, particularly in the posterior muscle groups. Future research with larger cohorts and prospective designs would be required to validate these dosimetric benefits and their relationship to MSK-related side effects post-radiotherapy.
Authors
- Emma Mauti (ORCID: https://orcid.org/0000-0002-1250-5984)
- Robert Bleakney (ORCID: https://orcid.org/0009-0000-4493-2676)
- Xiang Y. Ye (ORCID: https://orcid.org/0000-0003-2583-6974)
- Fei‐Fei Liu (ORCID: https://orcid.org/0000-0003-4344-6486)
- Melissa Weidman (ORCID: https://orcid.org/0000-0003-1241-8802)
- Leigh Conroy (ORCID: https://orcid.org/0000-0003-0055-3660)
- Zhihui Amy Liu (ORCID: https://orcid.org/0000-0003-1537-4868)
- Jennifer Croke (ORCID: https://orcid.org/0000-0002-7090-6313)
- Stephen Lowell Ciocon (ORCID: https://orcid.org/0000-0003-3210-6195)
- Wey L. Leong (ORCID: https://orcid.org/0000-0002-2892-5107)
- Randa Kamel (ORCID: https://orcid.org/0000-0002-6505-9359)
- Eugene Chang (ORCID: https://orcid.org/0000-0003-0124-929X)
- Jennifer Kwan (ORCID: https://orcid.org/0000-0003-2651-2402)
- Jennifer Michelle Jones (ORCID: https://orcid.org/0000-0002-8670-8514)
- Anne Koch (ORCID: https://orcid.org/0000-0002-3420-4875)
- Mohammad Arifur Rahman (ORCID: https://orcid.org/0000-0003-2618-1404)
- Grace Lee (ORCID: https://orcid.org/0000-0002-3123-0461)
- Antonio de la Pena Villarreal
Institutions
- University Health Network (CA)
- University of Toronto (CA)
- Toronto Rehabilitation Institute (CA)
- Princess Margaret Cancer Centre (CA)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.ctro.2025.101077
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00