Possible drug reaction with eosinophilia and systemic symptoms after spironolactone therapy for clinical hyperandrogenism: a case report
Clinicians should be aware of the rare but potentially serious risk of DRESS in patients treated with spironolactone. Prompt recognition, drug discontinuation, and supportive management are essential. Diagnostic confirmation with laboratory studies and skin biopsy should be pursued in suspected cases.
Authors
- Sandy Hoang (ORCID: https://orcid.org/0009-0008-1876-1234)
- Kathleen Brennan (ORCID: https://orcid.org/0000-0001-5880-3285)
- Danielle Strom
Institutions
- University of California, Los Angeles (US)
Publication Details
- Journal
- F&S Reports
- Published
- 2025-11-20
- DOI
- https://doi.org/10.1016/j.xfre.2025.11.004
- Citations
- 1
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.39