Predicting progressive vision loss in glaucoma patients using functional principal component analysis and electronic health records

A novel modeling approach combining FPCA with clinical data from EHR was able to model longitudinal clinical trajectories of glaucoma patients. This method is well-suited for modeling longitudinal healthcare data, handling sparse and irregular observation schedules with a varying number of inputs.

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Publication Details

Journal
Frontiers in Ophthalmology
Published
2025-11-19
DOI
https://doi.org/10.3389/fopht.2025.1632827
Primary Topic
Retinal Imaging and Analysis
Type
article
Field-Weighted Citation Impact
0.00

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article

Predicting progressive vision loss in glaucoma patients using functional principal component analysis and electronic health records

Sophia Ying Wang, Cody Carroll, Maxim Sivolella, Rithvik Krishna Donnipadu
Frontiers in Ophthalmology
Retinal Imaging and Analysis
article

Predicting progressive vision loss in glaucoma patients using functional principal component analysis and electronic health records

Sophia Ying Wang, Cody Carroll, Maxim Sivolella, Rithvik Krishna Donnipadu
article en

Abstract

A novel modeling approach combining FPCA with clinical data from EHR was able to model longitudinal clinical trajectories of glaucoma patients. This method is well-suited for modeling longitudinal healthcare data, handling sparse and irregular observation schedules with a varying number of inputs.

Frontiers in OphthalmologyVol. 5
Smith-Kettlewell Eye Research Institute (US), University of San Francisco (US)
Research to Prevent Blindness, American Glaucoma Society
Openalex Percentile: Top 50%
Retinal Imaging and Analysis
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