Safety and efficacy of short-term tirofiban combined with dual antiplatelet therapy after flow diverter placement for intracranial aneurysms: a multicenter retrospective study and nomogram for thromboembolic event prediction
Tirofiban combined with DAPT in flow diverter treatment for intracranial aneurysms demonstrated good safety without increasing bleeding risk, though its efficacy advantage over DAPT alone was not evident. The proposed nomogram enables individualized TEE risk prediction and supports personalized antiplatelet management.
Authors
- Fushun Xiao
- Xiangbo Liu (ORCID: https://orcid.org/0000-0001-5829-8127)
- Yunpeng Lin
- Jiwen Wang (ORCID: https://orcid.org/0000-0001-8568-7654)
- Chenguang Guo (ORCID: https://orcid.org/0000-0003-1013-9316)
- Xiaoning Liu (ORCID: https://orcid.org/0000-0003-3104-9109)
- Li Yang (ORCID: https://orcid.org/0000-0003-2716-3793)
- Yidi Wang (ORCID: https://orcid.org/0000-0002-0169-5081)
- Shiqing Mu (ORCID: https://orcid.org/0000-0002-1874-9277)
- Bingcheng Ren (ORCID: https://orcid.org/0000-0002-7891-8589)
Institutions
- Capital Medical University (CN)
- Tianjin Medical University General Hospital (CN)
- Tianjin Centers for Disease Control and Prevention (CN)
- Beijing Institute of Neurosurgery (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-11-19
- DOI
- https://doi.org/10.3389/fneur.2025.1689308
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00