Urinary lipid metabolites and progression of kidney disease in individuals with type 2 diabetes
Our findings reveal a strong association between urinary lipid metabolites and DKD progression. Specifically, urinary lipid profiling shows promise as a non-invasive tool to identify T2D patients at a high risk for rapid kidney function decline, outperforming the current clinical standard of albuminuria and eGFR.
Authors
- Caifeng Shi
- Yu Xiao (ORCID: https://orcid.org/0000-0002-7475-8442)
- Yang Zhou (ORCID: https://orcid.org/0000-0002-2859-1442)
- Xiaomei Wu (ORCID: https://orcid.org/0000-0002-4937-7680)
- Chunsun Dai
- Aiqin He
- Songyan Qin
Institutions
- Second Affiliated Hospital of Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-11-19
- DOI
- https://doi.org/10.3389/fendo.2025.1650498
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Nanjing Medical University