Decoding PFAS immunotoxicity: a NAMs-based comparison of short vs. long chains
Findings support a nuanced, compound-specific approach to PFAS risk assessment rather than a simple long- vs. short-chain distinction. In vitro NAMs provided mechanistic, human-relevant insights and reinforce their integration into regulatory frameworks.
Authors
- Marina Marinovich (ORCID: https://orcid.org/0000-0003-0625-8101)
- Valentina Galbiati (ORCID: https://orcid.org/0000-0003-3380-1501)
- Martina Iulini (ORCID: https://orcid.org/0000-0002-0275-6704)
- Emanuela Corsini (ORCID: https://orcid.org/0000-0002-6927-5956)
Institutions
- Ospedale San Paolo (IT)
Publication Details
- Journal
- Frontiers in Toxicology
- Published
- 2025-11-19
- DOI
- https://doi.org/10.3389/ftox.2025.1665163
- Citations
- 2
- Primary Topic
- Per- and polyfluoroalkyl substances research
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- European Food Safety Authority