Different kinetics of humoral response against individual antigens in the ovine model of Toxoplasma gondii infection and its pathological association
Our findings highlight distinct kinetics of specific antibody responses against selected <i>T. gondii</i> antigens in sheep, suggesting their value as markers of infection stage and pathology. rGra4Gra7 and rGra8 appear particularly promising both as diagnostic candidates and for exploring mechanisms of humoral modulation in ovine toxoplasmosis.
Authors
- Claudia Morsella
- D.P. Moore (ORCID: https://orcid.org/0000-0001-6735-3810)
- Luisa F. Mendoza Morales (ORCID: https://orcid.org/0000-0003-0253-3591)
- Valeria Scioli (ORCID: https://orcid.org/0009-0005-8436-4075)
- Lucía M. Campero
- Ana Cabrera (ORCID: https://orcid.org/0000-0003-2246-3471)
- Germán Cantón (ORCID: https://orcid.org/0000-0003-3494-8193)
- Valeria A. Sander (ORCID: https://orcid.org/0000-0002-3536-2007)
- Sergio O. Ángel (ORCID: https://orcid.org/0000-0003-4871-3408)
- Elizabeth Sosa (ORCID: https://orcid.org/0000-0003-2239-5966)
- Marina Clemente
- Ignacio Gual
- Paula M. Formigo
Institutions
- National University of Mar del Plata (AR)
- Centro para la Investigación en Sistemas Sostenibles de Producción Agropecuaria (CO)
- Instituto Tecnológico de Chascomús (AR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-11-19
- DOI
- https://doi.org/10.3389/fimmu.2025.1701645
- Primary Topic
- Toxoplasma gondii Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00