Evolution of continuous renal replacement therapy scenarios and the rise of anticoagulant-free continuous veno-venous hemodiafiltration
Both heparin and RCA are effective anticoagulation strategies in CRRT, with RCA preferred for its favorable safety profile. Nonetheless, nearly half of U.S. nephrologists report providing CRRT without anticoagulation. In our practice, we typically initiate CRRT without anticoagulation and reserve pharmacological agents for cases complicated by frequent filter clotting.
Authors
- Anuja Shah
- Ibrahim Elali (ORCID: https://orcid.org/0000-0002-1068-857X)
- Phuong‐Chi Pham (ORCID: https://orcid.org/0000-0001-7418-1658)
- Tiane Dai (ORCID: https://orcid.org/0000-0002-7238-3296)
- Ramanath Dukkipati (ORCID: https://orcid.org/0000-0001-9555-8389)
- Jenny I. Shen (ORCID: https://orcid.org/0000-0002-2993-403X)
- Chee Keong Chong
Institutions
- UCLA Medical Center (US)
- Los Angeles Medical Center (US)
- Olive View-UCLA Medical Center (US)
- Harbor–UCLA Medical Center (US)
Publication Details
- Journal
- Current Opinion in Nephrology & Hypertension
- Published
- 2025-11-19
- DOI
- https://doi.org/10.1097/mnh.0000000000001138
- Citations
- 1
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 1.43