Integrated metabolomics and gut microbiota analysis to explore the potential mechanism of levo-tetrahydropalmatine against ketamine addiction
The findings demonstrated that l-THP might serve as a promising intervention strategy for KET addiction by regulating serum and urine metabolism and gut microbiota.
Authors
- Keming Yun (ORCID: https://orcid.org/0000-0001-5934-4164)
- Hongliang Su (ORCID: https://orcid.org/0000-0002-4593-6078)
- Xingcui Gao
- Li Du (ORCID: https://orcid.org/0000-0002-4215-3801)
- Qing Ma
- Yan Du (ORCID: https://orcid.org/0000-0002-8306-3714)
Institutions
- Shanxi Medical University (CN)
- Shanxi Provincial Cancer Hospital (CN)
- National Institute for Radiological Protection (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-11-19
- DOI
- https://doi.org/10.3389/fphar.2025.1698866
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Key Research and Development Program of China